Getting More From the Gold You Already Trust

Image of technician in lab reading an LFA strip, with VigilantDX reader in background.

The Value and Limits of Vigilant Diagnostics Thermal Contrast Amplification™ Technology in Lateral Flow. Colloidal gold has been the workhorse label of lateral flow assays for decades. It’s cheap, it’s stable, it’s manufactured at enormous scale, and — critically — it sits inside assays that developers have already validated and, in many cases, already put…

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A Quick Update From the Bench at Vigilant Diagnostics

An illustrative example comparing a result with an optical LFA reader to the Vigilant TCA reader.

Our latest LED Thermal Contrast Amplification (TCA) reader achieved more than 16x the sensitivity of a commercially available, widely used optical lateral flow assay (LFA) reader running the same strip. For both R&D and clinical applications, sensitivity is often the gating factor — it determines which analytes you can detect, how early you can detect…

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Let’s Talk About Test Sensitivity

image of LFA test strip

In point-of-care diagnostics, sensitivity is back in the spotlight — not as an academic metric, but as a practical constraint. As respiratory panels expand (Covid, flu, RSV) and testing shifts closer to the patient, the industry is again confronting a familiar tension: speed and simplicity versus missed low-level positives. Visual lateral flow assays (LFA) remain…

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